Publications by authors named "M M Torrejais"
Objective: To evaluate the effects of magnifying the damage caused by obesity induced by monosodium glutamate, using a model of maternal periodontitis, on the structure of the anterior tibialis muscle of the offspring.
Materials And Methods: Twenty-four female Wistar rats were divided into four experimental groups: control (n = 6), obese (n = 6), control with periodontitis (n = 6) and obese with periodontitis (n = 6). At 78 days of life, the rats were mated with males without any experimental intervention.
An Early and Sustained Inflammatory State Induces Muscle Changes and Establishes Obesogenic Characteristics in Wistar Rats Exposed to the MSG-Induced Obesity Model.
Int J Mol Sci
March 2023
The model of obesity induced by monosodium glutamate cytotoxicity on the hypothalamic nuclei is widely used in the literature. However, MSG promotes persistent muscle changes and there is a significant lack of studies that seek to elucidate the mechanisms by which damage refractory to reversal is established. This study aimed to investigate the early and chronic effects of MSG induction of obesity upon systemic and muscular parameters of Wistar rats.
View Article and Find Full Text PDFWhole-Body Vibration Promotes Skeletal Muscle Restructuring and Reduced Obesogenic Effect of MSG in Wistar Rats.
Appl Biochem Biotechnol
August 2022
Article Synopsis
- - The study addresses the negative impacts of obesity on the locomotor system, which is increasingly common in Western societies due to rising rates of obesity and metabolic syndrome.
- - Whole-body vibration is highlighted as an effective and accessible form of exercise that can aid in the rehabilitation of obesity, particularly in a model induced by monosodium glutamate.
- - Key findings indicate that vibration therapy not only helps to reduce obesity-related issues and improve lipid profiles in the animals but also contributes to the recovery of muscle structure and oxidative capacity affected by obesity.
Glyphosate (GBH) is a worldwide consumption pesticide and is used in the formulation of Roundup®, one of the most commercialized herbicides in the world. Maternal exposure to this herbicide can promote changes and adaptations in the offspring; however, the effects on skeletal muscle are poorly understood. In this sense, the present study sought to evaluate the effect of exposure to GBH on the characteristics of the soleus (SOL) and extensor digitorum longus (EDL) muscles.
View Article and Find Full Text PDFStudy of muscle fibers of the extensor digitorium longus and soleus muscles of C57BL/6 females exposed to glyphosate during pregnancy and lactation.
Einstein (Sao Paulo)
August 2021
Objective: To evaluate the morphology and morphometry of the muscles extensor digitorium longus and soleus of C57BL/6 females, who were exposed to glyphosate during pregnancy and lactation.
Methods: Twelve female mice from the C57BL/6 lineage were used. After detection of pregnancy, they were divided into a Control Group, which received only water, and a Glyphosate Group, which received water with 0.