Publications by authors named "M M Thurnher"

Article Synopsis
  • Intracardiac thrombosis is frequent in patients with transthyretin amyloid cardiomyopathy (ATTR-CM), leading to potential risks like thromboembolic events, but the impact on brain health remains unclear.
  • A study involving 32 ATTR-CM patients showed significant findings using cerebral magnetic resonance imaging (cMRI), indicating they had more territorial infarcts, microbleeds, and Virchow-Robin spaces compared to matched controls.
  • The results suggest that even asymptomatic ATTR-CM patients might benefit from routine cMRI screening and consideration for anticoagulation therapy due to underlying cerebral vessel disease.
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We compared different LLMs, notably chatGPT, GPT4, and Google Bard and we tested whether their performance differs in subspeciality domains, in executing examinations from four different courses of the European Society of Neuroradiology (ESNR) notably anatomy/embryology, neuro-oncology, head and neck and pediatrics. Written exams of ESNR were used as input data, related to anatomy/embryology (30 questions), neuro-oncology (50 questions), head and neck (50 questions), and pediatrics (50 questions). All exams together, and each exam separately were introduced to the three LLMs: chatGPT 3.

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In non-muscle invasive bladder cancer, Bacillus Calmette-Guérin (BCG) responders benefit from strong Th1-type inflammatory and T cell responses mediating tumor rejection. However, the corresponding lack of anti-inflammatory Th2-type immunity impairs tissue repair in the bladder wall and facilitates the development of cystitis, causing urinary pain, urgency, incontinence, and frequency. Mechanistically, the leakage of the glycosaminoglycan (GAG) layer enables an influx of potassium ions, bacteria, and urine solutes towards the underlying bladder tissue, promoting chronic inflammation.

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