Introduction: Ischaemic stroke induces oxidative stress, mitochondrial damage, inflammation and senescence and the decrease of cognitive function. Vitamin D is a fat-soluble vitamin that has a neuroprotective effect to repair the function of the nervous system. The aim of this study is to investigate the effect of vitamin D on memory function, p16, p21 (senescence), and nerve growth factor (NGF) mRNA expression on the hippocampus after transient global cerebral ischemic.
View Article and Find Full Text PDFIntroduction: Ischaemic stroke induces oxidative stress with SOD2 downregulation, and BAX upregulation producing apoptosis. Vitamin D is a fat-soluble hormone that has a neuroprotective effect. The aim of this study is to elucidate the role of vitamin D in memory function, oxidative stress and apoptosis in transient global brain schaemic injury (TGBII) model.
View Article and Find Full Text PDFThe body mass index (BMI) has been promoted as a useful indicator for chronic energy deficiency, and to a lesser extent to indicate obesity. For the growing sector of elderly in developing countries, such as Indonesia, both issues are taking on public health relevance. The aging process leads to a progressive loss of height, and questions have been raised as to the appropriate value to include in the denominator of the BMI formula, WT(kg)/HT(m2), when applied in this age-group.
View Article and Find Full Text PDFJakarta is the capital and biggest city of Indonesia with a total population of 10 million. The National Census Office revealed a rapid increase in population through 1985 to 1990. This rapid increase has brought many devastating effects on various aspects of life such as housing, food stock and food production, health and environmental conditions, education, socio-economic and cultural life and political stability.
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