Future anxiety and the motives for postponing parenthood: generational time perspective and life satisfaction as mediators.

Introduction: Research to date has focused largely on the consequences of delayed parenting. However, little is known about the reasons and relevant mechanisms that are involved in people's decisions to delay parenthood. The aim of our study was to verify how anxiety about the future relates to the motives for deferred parenthood and how this relationship is mediated by generational time perspective and life satisfaction.

Impact of m6A Modification and Transcript Quantity on mRNA Composition in Plant Stress Granules.

Stress granules (SGs) are cytoplasmic structures that emerge in response to unfavorable environmental conditions. The mechanisms governing the accumulation of transcripts in SGs are only partially understood. Despite the recognized role of N6-methyladenosine (m6A) in plant transcriptome regulation, its impact on SGs' composition and assembly remains elusive.

MBNL splicing factors regulate the microtranscriptome of skeletal muscles.

Muscleblind like splicing regulators (MBNLs) govern various RNA-processing steps, including alternative splicing, polyadenylation, RNA stability and mRNA intracellular localization. In myotonic dystrophy type 1 (DM1), the most common muscular dystrophy in adults, MBNLs are sequestered on toxic RNA containing expanded CUG repeats, which leads to disruption of MBNL-regulated processes and disease features of DM1. Herein, we show the significance of MBNLs in regulating microtranscriptome dynamics during the postnatal development of skeletal muscles and in microRNA (miRNA) misregulation observed in mouse models and patients with DM1.

The mediating effect of maturity on anxiety and the motives for postponing parenthood.

Postponed parenthood is considered one of the most extensive changes in the process of family formation. Among the many reasons for deferred parenthood, those related to greater feelings of incompetence as a potential parent, self-focus, perceiving parenthood as a burden, fearing the changes that the birth of a child may bring to a person's life, financial insecurity, and worrying about the child's future seem particularly important. Since little is known about the motives for delayed parenthood in relation to anxiety and psychological maturity, the main goal of our study was to verify how these variables may be related to each other and whether maturity for parenthood mediates the direct association between anxiety and the motives for delayed parenthood.