Publications by authors named "M M Smorchkov"
Article Synopsis
- * Researchers created spidroin-based electrospun mats modified with ECM peptide motifs (RGD, IKVAV, VAEIDGIEL) to analyze their effects on the behavior of directly reprogrammed neural precursor cells (drNPCs).
- * Findings show that these modified mats help maintain the stemness of drNPCs while also influencing differentiation, with RGD promoting fewer but longer neurite-forming neurons, and IKVAV leading to more neurons but with shorter neurites, while still preserving neuroglial progenitor
Correlation of synovial caspase-3 concentration and the photodynamic effectiveness in osteoarthritis treatment.
Photodiagnosis Photodyn Ther
June 2020
Background: The present study focuses on investigation of Intra-articular PDT mechanisms for OA treatment. Also, a search for determination of the most effective dose of chlorin e6 (Ce6) for anti-inflammatory PDT of OA was carried out.
Methods: The study was carried out on laboratory animals (11 Chinchilla rabbits, 1 year, 2.
Gonarthritis photodynamic therapy with chlorin e6 derivatives.
Photodiagnosis Photodyn Ther
September 2016
Background: The new methods of osteoarthritis treatment are in constant demand due to the complexity of the early diagnosis and therapy. Specific features of Сhlorin e6 derivative (Ce6) accumulation in knee joint tissues and the efficiency of photodynamic therapy (PDT) of gonarthritis were studied.
Methods: The experimental research was conducted on the model of posttraumatic gonarthritis on rabbits.