Improving quality of magnetic resonance cholangiopancreaticography: esomeprazole versus ranitidine.

Background/aims: The aim of this study was to evaluate the effect of Ranitidine and Esomeprazole on the pancreatico-biliary tree and to define their role in improving visualization quality on magnetic resonance cholangiopancreaticography images.

Methodology: Magnetic resonance cholangiopancreaticography was done on 70 volunteers before and after using ranitidine for half of them and esomeprazole for the other half of the group. The images were evaluated for contrast effect (signal from stomach and duodenum), and image effect (conspicuousness) at various segments of pancreaticobiliary tree.

High prevalence of factor V Leiden in healthy Jordanian Arabs.

The prevalence of APC resistance in healthy Jordanian Arabs was studied. Between October 1996 through September 1997 a total of 400 healthy subjects were studied. There were 212 males and 188 females.

Hereditary thrombophilia among 217 consecutive patients with thromboembolic disease in Jordan.

This is a four-year prospective study on patients admitted or referred with thromboembolic disease to Jordan University Hospital or to the Thrombosis/Haemostasis Laboratory at the University of Jordan. The aim of the study was to find the relative prevalence of hereditary thrombophilia. For the purpose of this work, hereditary thrombophilia was diagnosed in the absence of an acquired cause of thrombophilia in addition to two of the following: 1) positive family history of thrombophilia, 2) confirmed same deficiency in a closely related family member, 3) the deficient protein is constantly below 2 SD of the normal mean on repeated testing.