Publications by authors named "M M Sanchez-Sanchez"

The inflammatory response has evolved as a protective mechanism against pathogens and tissue damage. However, chronic inflammation can occur, potentially leading to severe disease. Low-grade chronic inflammation is associated with obesity, and the Th1 cytokine profile plays an important role in this proinflammatory environment.

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Article Synopsis
  • Vector-borne diseases pose significant health challenges due to their complex control and zoonotic nature, especially in tropical regions where vector activity is year-round.
  • In Guadeloupe, a study analyzed blood samples from 46 outdoor dogs across five veterinary clinics to identify the presence of canine vector-borne pathogens, revealing that 30.4% of the dogs were infected.
  • The most common pathogens found were Coxiella burnetii (17.4%) and Dirofilaria immitis (8.7%), while there were no infections from other commonly tested pathogens, highlighting a knowledge gap in vector-borne diseases in the Caribbean.
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Bacteriocins are proteins with antimicrobial capacity produced by different bacteria. Developing bacteriocin-based technologies could be an effective strategy to address current problems in the pharmaceutical and food industries, including limited therapeutic options against superbug infections, foodborne diseases, and food spoilage microorganisms. The lactic acid bacteria Pediococcus pentosaceus are known producers of bacteriocins.

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Leishmaniosis, caused by phlebotomine sand fly-borne Leishmania spp., is a multi-host and zoonotic disease in tropical, subtropical and temperate climates, worldwide. Leishmania infantum is the only endemic pathogenic species in Europe, and exposure to this protozoan has previously been reported in a wide range of wild mammals, including felids.

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Cancer is a global health issue, increasingly prevalent and a leading cause of mortality. Despite extensive research, conventional treatments remain aggressive, often damaging healthy cells, and exhibit limited efficacy. Addressing drug resistance and enhancing treatment effectiveness are critical challenges in advancing cancer therapy.

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