Formulation of an innovative model for the bioeconomy.

Background: The bioeconomy, an evolving concept promoting sustainable use of renewable biological resources, confronts the challenge of balancing growth and sustainability across sectors like biotechnology, agriculture, and forestry. This study aims to elucidate the bioeconomy's dynamic nature, constructing a comprehensive theoretical model addressing these complexities.

Methodology: Through an extensive literature review, foundational elements for this model were identified: defining the core concept, delineating relevant variables, specifying assumptions and parameters, and depicting relationships through equations or diagrams.

Pediatric patients with lysosomal acid lipase deficiency.

Lysosomal acid lipase (LAL) deficiency is a rare, autosomal recessive disease caused by mutations in the LIPA gene, which produces cholesteryl ester and triglyceride accumulation predominantly in hepatocytes, adrenal glands, and gastrointestinal tract. We describe two new cases occurring in siblings, aged 5 and 7 years, who presented with hepatomegaly, dyslipidemia, and abnormal liver function. Percutaneous liver biopsy revealed portal inflammation, hypertrophic Kupffer cells with a foamy appearance and microvesicular steatosis with fibrosis.

SPECT/CT in Pleuroperitoneal Fistula Associated With Peritoneal Dialysis.

Pleuroperitoneal fistula is a rare entity found in approximately 1.6% of patients with peritoneal dialysis. The pathophysiology is unknown, and it is usually associated with increased abdominal pressure.