Publications by authors named "M M Reboredo"
Introduction: Multicenter research initiatives in Brazilian dialysis centers are scarce. We described the recruitment and implementation phases of the SARC-HD study, aimed at investigating sarcopenia and its impact on adverse clinical outcomes.
Methods: The SARC-HD is a cohort study being conducted with patients on hemodialysis in Brazil.
The impact of mechanical insufflation-exsufflation on the weaning success rate of tracheostomized patients on prolonged mechanical ventilation: a pilot and feasibility study of a randomized controlled trial.
Med Intensiva (Engl Ed)
January 2025
Objective: To evaluate the feasibility of adding mechanical insufflation-exsufflation (MI-E) to a weaning protocol for tracheostomized patients undergoing prolonged mechanical ventilation (MV).
Design: Single-center, open-label, randomized, controlled pilot and feasibility study.
Setting: Intensive care unit in Brazil.
Objectives: Here, we investigated the effects of hyperventilation on acute lung injury (ALI) in spontaneously breathing rats.
Methods: Wistar rats were randomized to receive either intraperitoneal lipopolysaccharides (LPS) or saline, and intravenous infusion of NH4Cl (to induce metabolic acidosis and hyperventilation) or saline. Four groups were established: control-control (C-C), control-hyperventilation (C-HV), LPS-control (LPS-C), and LPS-hyperventilation (LPS-HV).
Association between accelerometry and physical activity levels measured by questionnaires in patients on hemodialysis.
Disabil Rehabil
November 2024
Purpose: This study aimed to evaluate association of accelerometry data with physical activity levels (PAL) measured by three questionnaires and to investigate their ability to discriminate physically inactive from active patients on hemodialysis.
Materials And Methods: A cross-sectional study was conducted. PAL were assessed by accelerometry and questionnaires: Human Activity Profile (HAP), International Physical Activity Questionnaire (IPAQ), and 36-Item Short Form Health Survey (SF-36).
Article Synopsis
- Low muscle strength and function are linked to negative health outcomes in hemodialysis patients, yet reference values for muscle and physical performance tests are scarce.
- A large-scale analysis was conducted using baseline data from the SARC-HD study, focusing on handgrip strength, sit-to-stand tests, and gait speed, with results segmented by sex and age.
- Findings indicated that muscle strength and physical performance declined with age, with notable differences between males and females, and highlighted specific reference values that could serve as clinical markers for identifying patients at risk.