Publications by authors named "M M Rafik"

Article Synopsis
  • DNA-stabilized silver nanoclusters (Ag-DNAs) have flexible structures and light-emitting properties, but their chemical transformations are not fully understood.
  • A study used mass spectrometry to analyze the breakdown products of 21 types of Ag-DNAs, revealing that they can lose silver atoms and transition to states with fewer effective valence electrons.
  • Results indicated that Ag-DNAs stabilized by three DNA strands fragment more than those with two, and fragmentation patterns vary based on the DNA sequence, with simulations confirming that initial breakup respects electron-pairing rules.
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When compliance with infection control recommendations is non-optimal, hospitals may play an important role in hepatitis C (HCV) transmission. However, few studies have analyzed the nosocomial HCV acquisition risk based on detailed empirical data. Here, we used data from a prospective cohort study conducted on 500 patients in the Ain Shams hospital (Cairo, Egypt) in 2017 with the objective of identifying (i) high-risk patient profiles and (ii) transmission hotspots within the hospital.

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The corrosion of carbon steel infrastructure in acidic environments poses significant economic and safety challenges. Traditional inhibitors such as chromates are being phased out due to toxicity concerns. Thus, there is a need to develop effective and sustainable green alternatives.

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Near-infrared (NIR) emissive DNA-stabilized silver nanoclusters (Ag-DNAs) are promising fluorophores in the biological tissue transparency windows. Hundreds of NIR-emissive Ag-DNAs have recently been discovered, but their structure-property relationships remain poorly understood. Here, we investigate 19 different far-red and NIR emissive Ag-DNA species stabilized by 10-base DNA templates, including well-studied emitters whose compositions and chiroptical properties have never been reported before.

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We present chemical synthesis strategies for DNA-stabilized silver nanoclusters (Ag-DNAs) with near-infrared (NIR) emission in the biological tissue transparency windows. Elevated temperatures can significantly increase chemical yield of near-infrared nanoclusters. In most cases, basic pH favors near-infrared nanoclusters while micromolar amounts of NaCl inhibit their formation.

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