[Pathogenesis and treatment of hemocoagulation disorders in an acute necrotic pancreatitis].

Results of investigation of content of activated protein C, Intercellular Adhesion Molecule -1 (ICAM-1) and interleukin (IL)--18 in the patients with an acute pancreatitis were presented. At the hospital attendance the concentration of IL-18, ICAM-1 increase and the activated protein C level lowering were noted. The strict immediate correlation connection between serum blood level of IL-18, ICAM-1 and hematocrit and the reverse one--between these mediators concentration and the activated protein C content--were noted during all period of observation.