Publications by authors named "M M Obadia"
Background: Collateral circulation plays a key role in acute ischemic stroke. We sought to determine the association between the arterial collateral status, estimated by the Hypoperfusion Intensity Ratio (HIR) on perfusion MRI, and stroke etiology in anterior circulation large vessel occlusion (LVO).
Methods: We retrospectively analyzed anterior circulation LVO acute stroke patients with a baseline perfusion MRI performed within 24 h from symptom onset.
Article Synopsis
- The study investigated the clinical and radiological factors affecting the outcomes of acute ischemic stroke patients with isolated posterior cerebral artery (PCA) occlusion treated only with medical management.
- A total of 585 patients were analyzed, revealing that 56% experienced poor functional outcomes, which were linked to older age, higher NIHSS scores, larger infarct volumes, and not receiving intravenous thrombolysis (IVT).
- The research highlighted that factors like age, NIHSS score, infarct volume, and IVT status significantly influenced outcomes, while finding that complete recanalization after 24 hours improved recovery chances.
Article Synopsis
- - The study investigates the link between early reperfusion (ER) and visual outcomes in patients with central retinal artery occlusion (CRAO) or branch retinal artery occlusion (BRAO), finding that ER occurs in nearly 50% of cases.
- - Researchers included 70 patients, mostly with CRAO, and assessed visual outcomes at one month, revealing that those with ER had better visual acuity and quality of life compared to those without it.
- - The findings suggest that therapies aimed at enhancing ER could significantly improve clinical outcomes for patients suffering from CRAO or BRAO.
Background And Purpose: Disabling dystonia despite optimal medical treatment is common in Wilson disease (WD). No controlled study has evaluated the effect of deep brain stimulation (DBS) on dystonia related to WD. This study was undertaken to evaluate the efficacy of DBS on dystonia related to WD.
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- The study examined cerebral venous thrombosis (CVT) characteristics in elderly patients (65 years and older) across nine hospitals in the Paris-Ile-de-France region from 2011 to 2021.
- Researchers found that the annual incidence of CVT in this demographic was lower compared to the national average, with headaches and focal deficits being the most common initial symptoms.
- The results indicated that elderly patients had a distinct clinical profile, with higher rates of underlying conditions like cancer and a worse prognosis than younger adults, highlighting the need for specialized care in this age group.