Effects of Spinal Cord Stimulation in Patients with Small Fiber and Associated Comorbidities from Neuropathy After Multiple Etiologies.

The aim of this study was to evaluate the effects of spinal cord stimulation (SCS) on pain, neuropathic symptoms, and other health-related metrics in patients with chronic painful peripheral neuropathy (PN) from multiple etiologies. A prospective single center observational longitudinal cohort study assessed SCS efficacy from April 2023 to May 2024, with follow-ups at 2, 4, 6, and 12 months in 19 patients suffering from the painful polyneuropathy of diverse etiologies: diabetic (DPN), idiopathic (CIAP), chemotherapy-induced (CIPN), and others. Patients were implanted with a neurostimulator (WaveWriter Alpha, Boston Scientific Corporation, Valencia, CA, USA) and percutaneous leads targeting the lower limbs (T10-T11) and, if necessary, the upper limbs (C4-C7).

Triglyceride-Glucose Index as a Predictor of Cardiovascular Events in Psoriatic Patients on Systemic Therapy: A 150-Patient Observational Study.

Psoriasis is consistently associated with an elevated cardiovascular risk. However, biochemical parameters are needed to predict cardiovascular events in these patients. Therefore, we conducted a retrospective cohort study with psoriatic patients undergoing systemic treatment to analyze the value of the triglyceride-glucose (TyG) index in predicting the development of major adverse cardiovascular events (MACE).

Impact of ultra-processed food consumption during pregnancy on maternal and child health outcomes: A comprehensive narrative review of the past five years.

Background & Aims: Ultra-processed foods (UPF) are increasingly prevalent in modern diets and are associated with negative health outcomes such as chronic diseases due to their high processing and low nutrient density. Despite the potential impact of UPF intake during pregnancy on maternal and child health, studies in this area are limited. Therefore, this narrative comprehensive review aimed to identify associations between UPF consumption, categorized by the NOVA system, during pregnancy and maternal and child health outcomes over the past five years (2019-2024).

Modifiable cardiovascular risk factors in children at risk of acute myocardial infarction: A comprehensive review.

While acute myocardial infarction is rare in children, a part of the pediatric population is at a higher risk due to preexisting non-modifiable conditions. To mitigate the risk, modifiable risk factors such as unhealthy diet or sedentary lifestyle should be controlled from childhood, promoting healthy habits from the earliest stages. The primary purpose of this review is to assess the evidence on lifestyle/nutrition related modifiable risk factor intervention on the risk of acute myocardial infarction in children found in four databases, PubMed, Embase, Scopus and WoS.

Effects of Bisphenol A on the Risk of Developing Obesity.

Background: Every year the global incidence of obesity increases considerably and among the factors that favor it is bisphenol A (BPA), an endocrine disruptor widely used in plastics and omnipresent in many everyday objects.

Methods: A total of 19 studies published between 2018 and 2023 that addressed the relationship between BPA exposure and obesity were included in this review in order to better understand its behavior and mechanisms of action.

Results: The studies reviewed conclude that BPA is an obesogen that alters the function of hormonal receptors, promotes metabolic syndrome, affects certain genes, etc.