Effects of chlorpromazine on ischemic rat kidney: a functional and ultrastructural study.

The effects of chlorpromazine, an agent with inhibitory effects of calcium influx, phospholipase activation, and Na-K-ATPase, on preserving renal function and proximal tubular ultrastructure were evaluated in renal ischemia. After right nephrectomy chlorpromazine (0.025 mg) or 1 ml of 0.

Subcapsular urinoma: unusual form of "page kidney" in newborn.

The first case of renal hypertension resulting from a urinoma in a kidney secondary to vesicoureteral reflux from posterior urethral valves in a newborn is presented. High-pressure reflux resulted in formation of a subcapsular urinoma. Removal of the nonfunctioning "Page kidney" cured the persistent hypertension.

Effects of verapamil on preservation of renal function after ischemia: functional and ultrastructural study.

The effects of hypothermia and verapamil, a calcium antagonist, on preventing renal damage after 60 minutes of ischemia were studied in rats. Hypothermia alone provided the best protection, and pretreatment with verapamil failed to afford protective effects in normothermic and hypothermic ischemia, findings further supported by electron microscopic studies.

Suburethral diverticulum treatment by partial ablation.

The surgical technique of partial ablation was used to treat 34 patients with a symptomatic suburethral diverticulum. Results were excellent: Symptoms disappeared and the complications of urinary fistula and stress incontinence did not occur. There were no recurrences.

Urinary hydroxyproline excretion as a marker of osseous metastasis in carcinoma of the prostate.

Urinary hydroxyproline was elevated significantly in patients with untreated stage D prostatic carcinoma when compared to values in patients with benign prostatic hypertrophy and prostatic carcinoma without bony metastasis. Our results indicate that hydroxyproline may be a valuable marker in early staging, followup and evaluating treatment in prostatic cancer.