Publications by authors named "M M Marzi"
The antibiotic resistance and biofilm formation by bacterial pathogens has led to failure in infections elimination. This study aimed to assess the antibacterial and anti-biofilm properties of novel synthesized nitroimidazole compounds (8a-8o). In this study, nitroimidazole compounds were synthesized via the A3 coupling reaction of sample substrates in the presence of copper-doped silica cuprous sulfate (CDSCS).
View Article and Find Full Text PDFBackground And Aims: Celiac disease (CeD) affects 1-2% of the world's population. The aim of this study was to relate the incidence of CeD-related serological markers to symptoms, pathologies, and environmental exposure to wheat flour, given the number of flour mills present in the region.
Materials & Methods: Serum samples were collected from 537 inhabitants from a rural city.
Article Synopsis
- The study investigates how different diets (high-fat, high-carbohydrate, or a combination) affect the severity of damage caused by Shiga toxin 2 in the brains of mice, focusing on areas related to motor activity.
- Mice fed high-fat and high-carbohydrate diets experienced greater harm from Shiga toxin 2, with the worst outcomes noted in those on a combined diet, including neurodegeneration and impaired motor functions.
- The findings suggest that poor nutrition may worsen neurological damage in patients affected by Shiga toxin, indicating that diet can play a critical role in the severity of toxin-induced effects.
Molecular dynamics simulations were performed to investigate the structural and energetic features related to the direct binding of a short interfering RNA (siRNA) molecule on a silica nanoparticle functionalized with 3-aminopropyltriethoxysilane (APTES) groups, immersed in a sodium chloride aqueous solution at physiological concentration. Three different grafting densities of APTES were evaluated, namely, 2.7, 1.
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