Glucocorticoid receptors: The key of the response to steroid therapy in autoimmune hepatitis.

Aim Of The Study: This study was performed to investigate the hepatic expression of glucocorticoid receptors (GR) and 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1) in pediatric autoimmune hepatitis (AIH) patients and its relation to the steroid response.

Material And Methods: This study included 100 patients diagnosed with AIH on immunosuppressive therapy with different responses to treatment. The patients were subjected to full history taking and thorough clinical examination, laboratory investigations, abdominal ultrasound and liver biopsy for histopathological evaluation and assessment of the hepatic expression of GR and 11β-HSD1.

The evolving role of nursing informatics in the era of artificial intelligence.

Aim: This narrative review explores the integration of artificial intelligence (AI) into nursing informatics and examines its impact on nursing practice, healthcare delivery, education, and policy.

Background: Nursing informatics, which merges nursing science with information management and communication technologies, is crucial in modern healthcare. The emergence of AI presents opportunities to improve diagnostics, treatment, and healthcare resource management.

Unraveling the power of sense of coherence: a key predictor of symptom severity among depressive disorders clients.

Background: Despite advancements in therapies, the severity of depressive symptoms continues to challenge psychiatric nurses. However, research has indicated that a higher sense of coherence (SOC) can act as a protective factor against the development of diseases and promote faster recovery.

Aim: This study aimed to investigate whether SOC could serve as an indicator of depressive symptom severity among clients with depression.

Awareness and Attitudes of the Saudi Population Towards Bariatric Surgery in Saudi Arabia.

: Obesity is a growing public health concern worldwide, and Saudi Arabia faces rising rates of obesity-related conditions, including diabetes and cardiovascular diseases. Bariatric surgery is a recognized treatment for severe obesity, offering significant health benefits. This study evaluates the Saudi population's awareness and attitudes towards bariatric surgery, examining knowledge levels, perceptions, and potential barriers.