Glioblastoma: Overview and Magnetic Resonance Spectroscopy Analysis for Treatment.

Glioblastoma multiforme (GBM) is a very aggressive and fast-growing cancer of the brain that has a low life expectancy. Many new cases are diagnosed every year with each having a very poor prognosis. It is therefore of utmost concern to develop cures for such a devastating condition.

Concussion May Result in New-Onset Bipolar Disorder: A Case Report.

Emotional dysregulation following a concussion is well established. New onset of major psychiatric diseases such as bipolar disorder (BPD) post-concussion has not been investigated. BPD typically presents with an initial depressive episode followed by mania and concurrent depressive and manic states.

[A comprehensive assessment of brain perfusion data in patients with acute ischemic stroke for prediction of hemorrhagic transformation].

Unlabelled: A comprehensive assessment of brain perfusion data in connection with the Hemorrhagic Transformation Index (HTI) score to predict hemorrhagic transformation (HT) in acute ischemic stroke (AIS) patients.

Material And Methods: Based on propensity score matching, the authors selected retrospectively 21 case-control pairs from 71 consecutive patients with AIS in the middle cerebral artery territory. Brain computed tomography (CT) perfusion data with blood-brain barrier permeability assessment were obtained in all patients within 12 h after the onset.

The hemorrhagic transformation index score: a prediction tool in middle cerebral artery ischemic stroke.

Background: We aimed to develop a tool, the hemorrhagic transformation (HT) index (HTI), to predict any HT within 14 days after middle cerebral artery (MCA) stroke onset regardless of the intravenous recombinant tissue plasminogen activator (IV rtPA) use. That is especially important in the light of missing evidence-based data concerning the timing of anticoagulant resumption after stroke in patients with atrial fibrillation (AF).

Methods: We retrospectively analyzed 783 consecutive MCA stroke patients.

[Neurovisualisation predictors of malignant cerebral infarction and hemorrhagic transformation].

Neuroimaging plays a central role in the assessment of patients with acute ischemic stroke. Within a few minutes, modern multimodal imaging protocols can provide one with comprehensive information about prognosis, management, and outcome of the disease, and may detect changes in the intracranial structures reflecting severity of the ischemic injury depicted by four Ps: parenchyma (of the brain), pipes (i.e.