Publications by authors named "M M Iakubovskiĭ"

Morphofunctional and biochemical studies were carried out on bastard male rats (weight 200-240 g). The results showed that X-ray irradiation had induced structural alterations and elevation of lipid peroxidation in small intestine. Using of complex preparations defended this organ against pathological damages.

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State of immunologic and nonspecific resistance of the organism, ultra- and histostructure of the thymus, histopathology of the wall of experimental staph abscess reproduced in animals given low doses of the herbicide simazine for a long time have been studied. It is established that simazine induced the immunodeficiency state underlain by pathologic changes in the thymus. Against this background experimental abscesses developed more rapidly, alterative and exudative processes in their wall proceeding more intensively and proliferative ones--attenuating.

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Ultrastructural adenohypophysis-thyroid system investigation of Wistar male rats under conditions of chronic poisoning by Linuron herbicide and administration of thymohemin immunomodulator was performed. The release of thyrocyte fragments into the vascular lumen, electron-dense deposits in the area of vascular basal membrane, dilatation of endoplasmic reticulum cisternae as well as inhibition of Golgi complex in thyrocytes are observed in the thyroid exposed to Linuron; in the adenohypophysis under the same conditions swelling and splitting of microvessel basal membrane as well as the increase of biosynthetic and secretory thyrotrophic function can be seen. Thymohemin reduces the degree of degenerative processes in the thyroid gland.

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