The protective effect of naringenin on ulcerative colitis in mice through increasing Nrf2 pathway activity.

Ulcerative colitis (UC) is a chronic inflammatory disease with an increasing prevalence worldwide. Naringenin (NAR) has been proven effective in preventing UC, but its mechanism has not been fully elucidated. In this study, network pharmacology and bioinformatics methods are used to screen the genes associated with NAR and UC.

Preparation of Temperature Resistant Terpolymer Fracturing Fluid Thickener and Its Working Mechanism Study via Simulation Methods.

To enhance oil and gas recovery, a novel hydrophobic terpolymer was synthesized via free radical polymerization. The terpolymer consists of acrylamide, acrylic acid, and hydrophobic monomers, and is used as a hydraulic fracturing fluid thickener for freshwater environments. Hydrophobic groups were introduced into terpolymer to improve its tackiness and temperature resistance.

Therapeutic Effects of Alkaloids on Influenza: A Systematic Review and Meta-Analysis of Preclinical Studies.

Experimental evidence suggests that alkaloids have anti-influenza and anti-inflammatory effects. However, the risk of translating existing evidence into clinical practice is relatively high. We conducted a systematic review and meta-analysis of animal studies to evaluate the therapeutic effects of alkaloids in treating influenza, providing valuable references for future studies.

Effect of Ultra-High Temperature Degradation on the Physical Properties and Chemical Structure of an AMPS-Based Copolymer Oil-Well Cement Additive PADIM in Aqueous Solution.

2-acrylamido-2-methylpropane sulfonic acid (AMPS) based copolymer fluid loss agent is a kind of widely utilized additive in oil-well cement. However, when applied in ultra-high temperature (UHT) formation environment, its fluid loss control efficiency is significantly declined due to the thermal degradation behavior, and corresponding mechanism study is still lacking. Regarding the above issue, this work synthesized one representative copolymer fluid loss agent PADIM and investigated its thermal degradation mechanism in UHT aqueous environment, which was polymerized by AMPS, N, N-dimethylacrylamide (DMAA), itaconic acid (IA) and methacryloxyethyltrimethyl ammonium chloride (MTC).

Correlation between dietary vitamin B2 intake and helicobacter pylori infection in US adults: a cross-sectional study.

Objectives: Helicobacter pylori (H. pylori) infection is a widely recognized factor in causing inflammation in the stomach and significantly increases the likelihood of developing gastric cancer. The relation between intake of vitamin B2 in the diet and testing positive for Helicobacter pylori is still unclear.