Experimental and analytical study on axial behaviour of square corrugated concrete filled single and double skin tube stub columns.

Concrete-filled double-skin steel tubular (CFDST) columns have become widely utilized in building construction and bridges, thanks to their exceptional structural capabilities. Therefore, this study investigates the axial compressive behavior of square CFDST columns. The study aims to explore the influence of external and internal plate shapes (flat or corrugated plates) and different widths of internal steel tubes on the axial compressive behavior.

Optimization of a micro-scale air-liquid-interface model of human proximal airway epithelium for moderate throughput drug screening for SARS-CoV-2.

Background: Many respiratory viruses attack the airway epithelium and cause a wide spectrum of diseases for which we have limited therapies. To date, a few primary human stem cell-based models of the proximal airway have been reported for drug discovery but scaling them up to a higher throughput platform remains a significant challenge. As a result, most of the drug screening assays for respiratory viruses are performed on commercial cell line-based 2D cultures that provide limited translational ability.

Relationship of Structural Abnormalities of Papillary Muscles to the Site of Origin of Ventricular Arrhythmias.

Background: Arrhythmias originating from papillary muscles (PAPs) can be challenging when targeted with catheter ablation. The prevalence and impact of structural abnormalities on PAPs in patients with focal PAP arrhythmias is unknown.

Objectives: The purpose of this study was to analyze, in a consecutive patient series with focal PAP arrhythmias, the impact of structural abnormalities detected by multimodality imaging.