The HOPE4MCI study: AGB101 treatment slows progression of entorhinal cortex atrophy in ε4 non-carriers with mild cognitive impairment due to Alzheimer's disease.

Introduction: Hippocampal hyperactivity is a hallmark of prodromal Alzheimer's disease (AD) that predicts progression in patients with amnestic mild cognitive impairment (aMCI). AGB101 is an extended-release formulation of levetiracetam in the dose range previously demonstrated to normalize hippocampal activity and improve cognitive performance in aMCI. The HOPE4MCI study was a 78-week trial to assess the progression of MCI due to AD.

Bad habits that stick: adhesive tape use practices and beliefs.

Tape rolls are often used for multiple patients despite recommendations by manufacturers for single-patient use. We developed a survey to query Health Care Personnel about their tape use practices and beliefs and uncovered behaviors that put patients at risk for hospital-acquired infections due to tape use.

Investigating Fire-Atmosphere Interaction in a Forest Canopy Using Wavelets.

Wildland fire-atmosphere interaction generates complex turbulence patterns, organized across multiple scales, which inform fire-spread behaviour, firebrand transport, and smoke dispersion. Here, we utilize wavelet-based techniques to explore the characteristic temporal scales associated with coherent patterns in the measured temperature and the turbulent fluxes during a prescribed wind-driven (heading) surface fire beneath a forest canopy. We use temperature and velocity measurements from tower-mounted sonic anemometers at multiple heights.

Inpatient versus outpatient management of gestational hypertension or preeclampsia without severe features.

Objective: To comparematernal and neonatal outcomes in patients diagnosed with gestational hypertension or preeclampsia without severe features by outpatient versus inpatient management.

Materials And Methods: This was a single center, retrospective, cohort study of patients with hypertensive disorder of pregnancy (HDP) before 37 weeks' gestation from January 2014 to March 2022. Patients were triaged to inpatient or outpatient management at the discretion of their obstetrician.

CKD Progression following Acute Kidney Injury: A Secondary Analysis of the STARRT-AKI Trial.

Background: Chronic kidney disease (CKD) is a common complication after acute kidney injury (AKI). We aimed to evaluate whether RRT initiation strategy had an effect on CKD progression. Secondarily, we aimed to identify factors that influenced the development or progression of CKD following severe AKI.