Publications by authors named "M M Esnaola Y Rojas"
Background: Numerous challenges exist in effectively bridging theory and practice in the teaching and assessment of clinical reasoning, despite an abundance of theoretical models. This study compares clinical reasoning practices and decisions between medical students and expert clinicians using a problem-solving framework from the learning sciences, which identifies clinical reasoning as distinct, observable actions in clinical case solving. We examined students at various training stages against expert clinicians to address the research question: How do expert clinicians and medical students differ in their practices and decisions during the diagnostic process?.
View Article and Find Full Text PDFThe yellow mealworm, Tenebrio molitor L., is one of the most important industrialized insects worldwide. As a poikilotherm, T.
View Article and Find Full Text PDFThe Fifth Annual Symposium of the Midwest Aging Consortium.
J Gerontol A Biol Sci Med Sci
December 2024
As the healthcare burden caused by an increasingly aging population rapidly rises, a pressing need exists for innovative geroscience research that can elucidate aging mechanisms and precipitate the development of therapeutic interventions to support healthy aging. The Fifth Annual Midwest Aging Consortium Aging Research symposium, held from April 28-30, 2024, was hosted by The Ohio State University in Columbus, Ohio and featured presentations from investigators across the Midwestern United States. This report summarizes the research presented at the symposium, whose topics included cellular senescence and the aging brain, metabolism and metabolic interventions, nutrition, redox mechanisms and biomarkers, and stress mechanisms.
View Article and Find Full Text PDFAims: Remodeling of the extracellular matrix (ECM) is critical for effective wound healing and maintaining organ homeostasis. The ECM of soft tissues, including cardiac, contains embedded nanovesicles; or matrix-bound nanovesicles (MBV). The luminal cargo of MBV consists of lipids, microRNAs (miRNAs), and proteins that influence the function of immune and stromal cells.
View Article and Find Full Text PDFArticle Synopsis
- Bovine babesiosis, a disease caused by a parasite carried by ticks, poses a global threat to cattle, highlighting the need for new vaccines.
- Researchers identified immune-subdominant (ISD) antigens, specifically rRAP-1 NT and rRRA, which elicited lower antibody responses compared to dominant antigens in previously protected cattle.
- Vaccination of cattle with rRRA and rRAP-1 NT showed promising results, as most immunized animals developed strong immune responses and experienced a delay in sickness symptoms when exposed to the parasite, indicating the potential for these ISD antigens in developing future vaccines.