Publications by authors named "M M Danila"

Black chokeberry ( Elliot) represents a rich source of dietary polyphenols and other bioactive phytochemicals with pleiotropic beneficial cardiovascular effects. The present study was aimed at evaluating the ex vivo effects of two black chokeberry extracts (BChEs), obtained from either dry (DryAr) or frozen (FrozAr) berries, on oxidative stress and vascular function in mice aortic rings after incubation with angiotensin 2 (Ang 2), lipopolysaccharide (LPS) and glucose (GLUC) in order to mimic renin-angiotensin system activation, inflammation and hyperglycemia.

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The global burden of cancer as a major cause of death and invalidity has been constantly increasing in the past decades. Monoamine oxidases (MAO) with two isoforms, MAO-A and MAO-B, are mammalian mitochondrial enzymes responsible for the oxidative deamination of neurotransmitters and amines in the central nervous system and peripheral tissues with the constant generation of hydrogen peroxide as the main deleterious ancillary product. However, given the complexity of cancer biology, MAO involvement in tumorigenesis is multifaceted with different tumors displaying either an increased or decreased MAO profile.

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Article Synopsis
  • There is growing interest in using point of care ultrasound (POCUS) as a teaching tool in medical courses, particularly for cardiac anatomy and physiology; however, few studies have explored team-based learning (TBL) approaches for this topic.
  • This study introduced a novel TBL exercise called Team-Based Learning - Ultrasound (TBL-US) for first-year medical students, comprising phases such as preparation, team readiness, image acquisition, and knowledge assessment, facilitated by trained second-year students.
  • Results showed significant improvements in students’ knowledge of cardiac POCUS and cardiovascular content, with enhanced final exam scores for TBL-US participants compared to non-participants, indicating that this method effectively supports learning in preclinical medical education.
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Coronavirus disease 2019 (COVID-19) vaccine uptake among individuals with rheumatic conditions remains low despite heightened risk for related adverse outcomes. This is especially pronounced among historically marginalized populations who suffered disproportionately from the COVID-19 pandemic. Among the myriad of reasons for low vaccine uptake, mistrust in the healthcare system, misinformation related to the vaccine development process, fear of rheumatic disease flares, and inconsistent physician recommendations, are highlighted.

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