Totally implantable venous access devices: A restrospective analysis of morbidity and risk factors in a hospital with multi-technique approaches.

Background: Totally implantable venous central access devices (TIVADs) can be implanted by open surgery or by direct puncture in the subclavian (ScV), internal jugular (IJV) or cephalic (CephV) veins.

Methods: A retrospective study was conducted in 201 patients. Thirty-day follow-up data was analyzed to compare the outcomes of different techniques and evaluation of risk factors.

Coordinated conformational changes in P450 decarboxylases enable hydrocarbons production from renewable feedstocks.

Fatty acid peroxygenases have emerged as promising biocatalysts for hydrocarbon biosynthesis due to their ability to perform C-C scission, producing olefins - key building blocks for sustainable materials and fuels. These enzymes operate through non-canonical and complex mechanisms that yield a bifurcated chemoselectivity between hydroxylation and decarboxylation. In this study, we elucidate structural features in P450 decarboxylases that enable the catalysis of unsaturated substrates, expanding the mechanistic pathways for decarboxylation reaction.

Topical application of the ethanol extract and the hydroethanolic fraction of ripe Solanum lycocarpum A. St. Hil. fruit improves the healing of excisional wounds.

Purpose: To evaluate the effect of the topical application of the ethanol extract (EESL) and the hydroethanolic fraction (HFSL) of ripe Solanum lycocarpum fruit on the healing of experimentally-induced wounds in mice.

Methods: The EESL and HFSL obtained from ripe fruit of the species S. lycocarpum were obtained by percolation with ethanol.

TRPV4 modulates inflammatory responses and apoptosis in enteric glial cells triggered by Clostridioides difficile toxins A and B.

Clostridioides difficile, a spore-forming anaerobic bacterium, is the primary cause of hospital antibiotic-associated diarrhea. Key virulence factors, toxins A (TcdA) and B (TcdB), significantly contribute to C. difficile infection (CDI).

First Record of Tropical Sod Webworm on Turfgrass in Brazil.

Climate change and anthropogenic disturbance in agricultural production systems can facilitate shifts in the distribution of arthropod pest species and in the range of plant hosts on which they feed. This study presents the first record of Tropical Sod Webworm (TSW), Herpetogramma phaeopteralis Guenée (Lepidoptera: Crambidae: Spilomelinae), on native or nativized species of the genus Axonopus (Poaceae) in Brazil. The occurrence of population outbreaks of this species was observed in March and April of 2024 among smallholder cattle farmers in Capão Alto and Campo Belo do Sul, both municipalities situated in the highlands of Santa Catarina State, southern Brazil.