Influence of Conservative or Invasive Treatments on the Occurrence of Sequelae in Permanent Successors After Injuries in the Support Tissues of Incisors Deciduous Teeth: A Cohort Study.

Objective: To assess the influence of conservative or invasive treatments on the appearance of sequelae in permanent successor teeth (SPT) after injuries in the support tissues of anterior deciduous teeth (ISTDT).

Methods: This cohort study accompanied 52 children with ISTDT up to the complete eruption of the permanent successor to investigate the presence or not of SPT. Trauma was clinically evaluated according to the International Association for Dental Traumatology.

Agathisflavone Inhibits Viability and Modulates the Expression of miR-125b, miR-155, IL-6, and Arginase in Glioblastoma Cells and Microglia/Macrophage Activation.

Glioblastomas (GBM) are malignant tumours with poor prognosis. Treatment involves chemotherapy and/or radiotherapy; however, there is currently no standard treatment for recurrence, and prognosis remains unfavourable. Inflammatory mediators and microRNAs (miRNAs) influence the aggressiveness of GBM, being involved in the communication with the cells of the tumour parenchyma, including microglia/macrophages, and maintaining an immunosuppressive microenvironment.

Can microplastic pollution be affected by beach nourishment? Assessment in intertidal sediment and bivalves.

Several methods can be used to mitigate coastal erosion, and one of the leading solutions is known as beach nourishment (BN), which involves using dredged material for nourishment, adding sand to extend an eroding beach. Although it has many advantages, the environmental impacts of BN remain poorly understood, especially on plastic pollution, which had not been investigated until this study. We aimed to compare the abundance and distribution of microplastics (MPs) found in intertidal sediments and specimens of the bivalve mollusks Crassostrea brasiliana, Mytella strigata, Perna perna, and Tivela mactroides, collected in two beaches of Vitoria, Southeast of Brazil (da Costa et al.

Safety and efficacy of three alternative regimens against relapsing Plasmodium vivax malaria in glucose 6-phosphate dehydrogenase deficient patients in the Brazilian Amazon (ALTPRIM).

Background: Daily primaquine-induced hemolysis is a common cause of complications during Plasmodium vivax malaria treatment in individuals with glucose 6-phosphate dehydrogenase deficiency (G6PDd). Alternative regimens balancing safety and efficacy are needed.

Methods: G6PDd participants with P.