Publications by authors named "M M Chow"
Context: There has been growing interest in the role of complementary and alternative medicine (CAM) as part of end-of-life care.
Objectives: This study prospectively examined the prevalence, predictors and outcomes of ingestible CAM use among cancer patients in their last year of life in Singapore.
Methods: This study (N=427) utilized data across 12 months (4 time points) prior to patient death.
Point mutations in the ligand binding domain of retinoic acid receptor alpha (RARα) are linked to breast fibroepithelial tumor development, but their role in solid tumorigenesis is unclear. In this study, we assessed the functional effects of known RARα mutations on retinoic acid signaling using biochemical and cellular assays. All tested mutants exhibited reduced transcriptional activity compared to wild-type RARα and showed a dominant negative effect, a feature associated with developmental defects and tumor formation.
View Article and Find Full Text PDFBackground: Psoriasis is a chronic inflammatory skin disease often associated with obesity. Psoriasis therapies may be less effective in obese patients. The purpose of this expert consensus panel is to evaluate the relationship between obesity and efficacy of psoriasis therapies, thereby optimizing patient care.
View Article and Find Full Text PDFBackground And Purpose: Flow diversion (FD) has expanded beyond initial indications (proximal carotid artery aneurysms) to include distal circulation aneurysms (on the anterior, middle, or posterior cerebral arteries). Our objective was to examine results obtained from aneurysms in these locations in the Flow Diversion in the Treatment of Intracranial Aneurysms Trial (FIAT) which compared FD with alternative standard management options (ASMO).
Materials And Methods: FIAT was an all-inclusive parallel-group 1:1 randomized study comparing FD with one of 4 ASMOs (coiling +/-stenting, parent vessel occlusion (PVO), clipping, or observation, pre-specified by clinical judgment).
Article Synopsis
- - Language plays a critical role in math education, impacting how knowledge is taught and learned, especially in the context of bilingual and multilingual classrooms.
- - The paper details the process of compiling a bilingual corpus of classroom discourse in math lessons conducted in both Chinese and English for primary school students.
- - It suggests that analyzing this longitudinal data can help understand the effects of bilingual interactions on teaching and learning, enabling teachers to improve their instructional strategies and student outcomes.