Publications by authors named "M M Chaves"
Article Synopsis
- Subjective cognitive decline (SCD) involves cognitive complaints in cognitively unimpaired individuals, with sleep disturbances potentially linked to these complaints.
- The study included participants over 65 with cognitive complaints, excluding those with significant psychiatric or medical issues, and used various assessments to track their conditions over 12 months.
- Analysis of 47 participants revealed that while sleep quality (measured by PSQI) correlated with anxiety levels, there were no significant links between sleep complaints and cognitive measures or demographics.
Article Synopsis
- Mild Behavioral Impairment (MBI) is being assessed in Brazilian individuals with early cognitive decline (SCD and MCI) to understand neuropsychiatric symptoms better.
- The study utilized the MBI-Checklist (MBI-C) among 47 participants to explore correlations with other psychological metrics like the Neuropsychiatric Inventory and Geriatric Depression Scale.
- Results indicated significant correlations between informants' observations and other assessments, while participant and informant MBI-C scores had different correlations, suggesting varying perceptions of neuropsychiatric symptoms.
Background: The WHO states that antivenom is the only safe and effective treatment to neutralize snake venom. Snakebite antivenom typically involves horse hyperimmunization with crude venom and Freund's adjuvant.
Methods: In the current work, we analyzed the ascorbyl palmitate liquid crystal structure with snake protein or PLA2, the carrier charge capacity, and we evaluated the immune response induced by the enzyme P9a(Cdt-PLA2) formulated in a nanostructure using CpG-ODN, determining the titer of IgG antibodies.
The Influence of Ovarian-Derived Extracellular Vesicles in Reproduction.
Adv Anat Embryol Cell Biol
January 2025
In this chapter, we explore the multifaceted roles of extracellular vesicles (EVs) in ovarian biology, focusing on their contributions to folliculogenesis, oocyte competence, corpus luteum function, and immune response regulation. EVs, particularly those derived from follicular fluid (ffEVs), are crucial mediators of cell-to-cell communication within the ovarian follicle, influencing processes such as meiotic progression, stress response, and hormonal regulation. We review preexisting literature, highlighting key findings on the molecular cargo of EVs, such as miRNAs and proteins, and their involvement in regulating the function of the follicle cells.
View Article and Find Full Text PDFCircadian clocks form a fundamental mechanism that promotes the correct behavior of many cellular and molecular processes by synchronizing them on a 24 h period. However, the circadian cycles remain difficult to describe mathematically. To overcome this problem, we first propose a segmentation of the circadian cycle into eight stages based on the levels of expression of the core clock components CLOCK:BMAL1, REV-ERB and PER:CRY.
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