Laser based-powder bed fusion (LB-PBF) enables fast, efficient, and cost-effective production of high-performing products. While advanced functionalities are often derived from geometric complexity, the capability to tailor material properties also offers significant opportunities for technical innovation across many fields. This study explores the optimization of the LB-PBF process parameters for producing Ti6Al4V titanium alloy parts with controlled porosity.
View Article and Find Full Text PDFThe claustrum is a brain structure that remains shrouded in mystery due to the limited understanding of its cellular structure, neural pathways, functionality and physiological aspects. Significant research has unveiled connections spanning from the claustrum to the entire cortex as well as subcortical areas. This widespread connectivity has led to speculations of its role in integrating information from different brain regions, possibly contributing to processes such as attention, consciousness, learning and memory.
View Article and Find Full Text PDFplants produce two major classes of valuable sterol-derived natural products-steroidal glycoalkaloids and steroidal saponins-from a common cholesterol precursor. Attempts to heterologously produce these molecules have consistently failed, although the genes responsible for each biosynthetic step have been identified. Here we identify a cellulose synthase-like protein, an unexpected biosynthetic component that interacts with the early pathway enzymes, enabling steroidal scaffolds production in plants.
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