Publications by authors named "M M Bills"
Article Synopsis
- - The study explored the effects of injecting phosphorus-32 (P) microparticles into pancreatic tumors during chemotherapy (FOLFIRINOX) to improve poor blood flow—which hinders treatment responses—in patients with locally advanced pancreatic cancer (LAPC).
- - Out of 20 patients, the results showed a significant decrease in tumor size and increased vascularity after P implantation, with 25% achieving tumor downstaging and four patients opting for surgery.
- - Most patients (75%) remained alive after an average follow-up of 11.2 months, but the study found no significant difference in overall survival between patients who showed increased tumor blood flow and those who did not.
Purpose: Excellent metabolic improvement following one anastomosis gastric bypass (OAGB) remains compromised by the risk of esophageal bile reflux and theoretical carcinogenic potential. No 'gold standard' investigation exists for esophageal bile reflux, with diverse methods employed in the few studies evaluating it post-obesity surgery. As such, data on the incidence and severity of esophageal bile reflux is limited, with comparative studies lacking.
View Article and Find Full Text PDFThe global COVID-19 pandemic has challenged healthcare, aged care and palliative care provision in ways previously unimaginable. In Australia, this has been felt particularly amongst our most vulnerable members of society, those residing in residential aged care. Currently representing the majority (75%) of COVID-19 deaths and health-care worker infections, this vulnerable sector has borne the greatest impact.
View Article and Find Full Text PDFTumors differ from normal tissues in several meaningful ways including cellular size, morphology, and protein expression, which will accordingly change the refractive index and the size/morphology of cells. There are also important differences in tissue organization and unique tissue specific cell densities. Instead of time-consuming and labor-intensive histology involving the use of a benchtop microscope, a plot of Mie scattering intensities at fixed wavelength against scattering angle, which we referred to as "Mie spectrum," is suggested as an alternative to identify tumor from normal tissues.
View Article and Find Full Text PDFBackground: Energy-dense formulae are often provided to critically ill patients with enteral feed intolerance with the aim of increasing energy delivery, yet the effect on gastric emptying is unknown. The rate of gastric emptying of a standard compared with an energy-dense formula was quantified in critically ill patients.
Methods: Mechanically ventilated adults were randomized to receive radiolabeled intragastric infusions of 200 mL standard (1 kcal/mL) or 100 mL energy-dense (2 kcal/mL) enteral formulae on consecutive days in this noninferiority, blinded, crossover trial.