Introduction: Radiography students experience high levels of stress due to demanding academic studies and clinical training. Expanding this study to different settings could provide insights for customized interventions. This study aims to investigate the prevalence and causes of stress experienced by radiography students across university settings in Egypt, the UAE, and Jordan, with particular attention to gender-based differences.
View Article and Find Full Text PDFThe site-specific antibody-drug conjugates (ADCs), particularly those utilizing the engineered cysteine in Fc fragments of mAbs (THIOMAB™ antibodies), have emerged as a novel class of biotherapeutics for cancer treatment. The engineered cysteine residues in these antibodies are capped by cysteine or glutathione through a disulfide bond. Prior to conjugation with linker-payloads, these caps need to be removed through a reduction process.
View Article and Find Full Text PDFPosttranslational modifications (PTMs) are potential critical quality attributes in biotherapeutic development, as they can affect drug efficacy and safety. Tyrosine sulfation plays a critical role in protein-protein interactions and has been found on many surface receptors as well as antibody complementarity-determining regions (CDR). However, the presence and function of tyrosine sulfation in therapeutic proteins have not been broadly investigated due to difficulties in detecting the modification.
View Article and Find Full Text PDFA viable tactic to effectively address the climate crisis is the production of renewable fuels via photocatalytic reactions using solar energy and available resources like carbon dioxide (CO) and water. Organic polymer material-based photocatalytic materials are thought to be one way to convert solar energy into valuable chemicals and other solar fuels. The use of porous organic polymers (POPs) for CO fixation and capture and sequestration to produce beneficial compounds to reduce global warming is still receiving a lot of interest.
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