Efficacy of oral amantadine among patients hospitalised with COVID-19: A randomised, double-blind, placebo-controlled, multicentre study.

Background: Amantadine has been proposed as a treatment for COVID-19 because it shows anti-SARS-CoV-2 activity in vitro. However, to date, no controlled study has assessed the safety and efficacy of amantadine in COVID-19.

Research Question: Whether amantadine is effective and safe among patients with different COVID-19 severity classifications.

AQM based on the queue length: A real-network study.

Active Queue Management (AQM) is recommended by Internet Engineering Task Force to mitigate the bufferbloat phenomenon in the Internet. In this paper, we show the results of comprehensive measurements carried out in our university network, in which a device with an AQM algorithm, designed and programmed for this purpose, was running. The implemented AQM algorithm was based on the dropping function, i.

Optimal Motion Planning in GPS-Denied Environments Using Nonlinear Model Predictive Horizon.

Navigating robotic systems autonomously through unknown, dynamic and GPS-denied environments is a challenging task. One requirement of this is a path planner which provides safe trajectories in real-world conditions such as nonlinear vehicle dynamics, real-time computation requirements, complex 3D environments, and moving obstacles. This paper presents a methodological motion planning approach which integrates a novel local path planning approach with a graph-based planner to enable an autonomous vehicle (here a drone) to navigate through GPS-denied subterranean environments.

Asthma-COPD Overlap-A Discordance Between Patient Populations Defined by Different Diagnostic Criteria.

Background: The concordance between asthma-chronic obstructive pulmonary disease overlap (ACO) defined according to Global Inititative for Asthma (GINA)/Global Initiative for Chronic Obstructive Lung Disease (GOLD) and other diagnostic criteria is unknown.

Objective: To assess the concordance between different ACO definitions and to estimate the definition-based ACO prevalence and characteristics.

Methods: A prospective, real-life study based on a 32-item data set was performed in a mixed population of patients with asthma and chronic obstructive pulmonary disease (COPD).

Clear Cell Carcinoma of the abdominal wall.

Background: Clear cell carcinoma in scars after cesarean section is extremely rare, with only 22 cases reported in the literature. Management of this condition needs to be further explored. Here, we report of a patient with clear cell carcinoma of the abdominal wall that developed 35 years after cesarean section.