Publications by authors named "M M Backonja"
Objective: This article synthesizes current knowledge on neuropathic pain, with a brief review of mechanisms, diagnostic approaches, and treatment strategies to help neurologists provide effective and individualized care for patients with this complex condition.
Latest Developments: The most promising developments in peripheral neuropathic pain are related to the molecular biology of the peripheral nervous system. Systematic molecular and genetic analyses of peripheral nerve terminals and dorsal root ganglia have advanced our understanding of the genetics of function and disease of peripheral nerves, as well as their physiology and clinical manifestations.
Sustained widespread deployment of clinically and cost-effective models of integrated pain care could be bolstered by optimally aligning shared stakeholder values.
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- The article explores the use of qualitative and quantitative sensory testing (QQST) to better understand neuropathic pain by merging personal experiences with measurable data.
- It highlights the importance of identifying signs of sensory abnormalities and standardizing how data is collected to optimize this testing approach.
- The QQST method is presented as a key part of the Sensory Evaluation Network, which aims to bring together global experts to improve sensory evaluation techniques.
Background: To estimate the effects on pain of two medications (low-dose naltrexone and gabapentin) compared to placebo among people with HIV (PWH) with heavy alcohol use and chronic pain.
Methods: We conducted a pilot, randomized, double-blinded, 3-arm study of PWH with chronic pain and past-year heavy alcohol use in 2021. Participants were recruited in St.