Comparative evaluation of antifungal susceptibility testing methods of invasive Candida species and detection of FKS genes mutations in caspofungin intermediate and resistant isolates.

Background: Fungal invasive infections caused by Candida species pose a substantial public health risk with limited therapeutic options. Antifungal susceptibility testing (AFST) is necessary to optimize the therapy. The study aimed to compare different AFST methods of Candida spp.

First case report on Bickerstaff brainstem encephalitis in a young adult from Syria: Bridging clinical knowledge and practice.

Bickerstaff Brainstem Encephalitis (BBE) is a rare immunologic condition characterized by CNS inflammation, presenting with ataxia, external ophthalmoplegia, altered consciousness, and quadriplegia. A 25-year-old male with no significant medical history exhibited symptoms of blurred vision, diplopia, facial numbness, and imbalance following a respiratory infection. Brain MRI revealed hyperintense lesions in the cerebral peduncle and pons on T2-weighted/FLAIR sequences but not on T1-weighted sequences, indicative of demyelination.

Rehabilitation of N, N'-methylenebisacrylamide-induced DNA destruction in the testis of adult rats by adipose-derived mesenchymal stem cells and conditional medium.

Environmental pollutant acrylamide has toxic effect on human health. Numerous industries such as the paper, and cosmetics, use acrylamide in their manufacturing. In certain foods, acrylamide arises at extremely high temperatures.

Carob fruit extract as naturally products corrosion inhibitor for copper-nickel alloys in brine solutions.

Copper-nickel alloys are the preferred material for desalination facilities and condensers and heat exchangers that use saltwater as a coolant. The eco-friendly compounds especially Carob fruit extract (CFE) has emerged as excessive green corrosion inhibitor for alloys. Cu-Ni alloys are widely used in various industries due to their excellent corrosion resistance.

The cytotoxic activities of the major diterpene extracted from Salvia multicaulis (Bardakosh) are mediated by the regulation of heat-shock response and fatty acid metabolism pathways in human leukemia cells.

Background: Leukemia is one of the most lethal cancers worldwide and represents the sixth-leading cause of cancer deaths. The results of leukemia treatment have not been as positive as desired, and recurrence is common.

Purpose: Thus, there is an urgent requirement for the development of new therapeutic drugs.