Publications by authors named "M M Althobiti"
Article Synopsis
- Insulin-like growth factor-I (IGF-I) is vital for regulating cell growth and has strong links to various cancers, making its signaling pathway a potential target for new cancer treatments.
- The study utilized evolutionary data and protein analysis to create new IGF-1 peptide variants, revealing important structural features and interactions with cell surface receptors.
- Findings indicate that these new peptide variants could serve as effective tools in designing anticancer therapies by mimicking IGF-1, ultimately enhancing our understanding of its role in cancer progression.
Article Synopsis
- - Anopheles funestus mosquitoes are becoming key players in spreading malaria in sub-Saharan Africa, and targeting trehalase, an enzyme vital for their flight and stress responses, could help manage this issue.
- - Researchers screened 1,900 natural compounds from the ZINC database against the A. funestus trehalase protein using in-silico tools and identified five compounds with strong binding affinities and favorable drug-like properties.
- - The identified compounds show potential as inhibitors for the trehalase protein, but further experimental studies are necessary to enhance their effectiveness as malaria management options.
Insight into hematological parameters of petrol station workers.
Eur Rev Med Pharmacol Sci
April 2024
Objective: Benzene is one of the major carcinogenic factors that can affect liver, kidneys, and lungs. Chronic inhalation of benzene vapor by petrol stations workers has been shown to have an impact on hematological parameters; thus, the present study aimed to investigate the effect of benzene exposure on petrol station workers.
Subjects And Methods: The study involved 99 participants, 50 of whom have been exposed to benzene and 49 of whom have not (control).
The current study aimed to assess the efficacy of ozone therapy in the treatment of stage II and stage III periodontitis. This prospective split-mouth study selected patients who were diagnosed with either stage II or stage III periodontitis. All patients were treated with scaling and root-planing (SRP) on the control side and SRP with ozone therapy on the test side.
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