[Biodegradable devices for annulus fibrosus defect closure after lumbar discectomy].

Objective: To study the properties of materials and select the most suitable one for appropriate device covering annulus fibrosus defect after lumbar discectomy.

Material And Methods: Prototype devices made of poly(L-)lactide, polycaprolactone (PLC) and copolymers of(L-)lactide and ε-caprolactone (LCL) without prior purification were used. Sponge materials were prepared using 1.

[Interbody cage implantation in cadaveric model of the ram spine: biomechanical tests].

Objective: To evaluate the mechanical properties of poly(L-lactide) cage prototypes on cadaveric models of the lumbar spine ram model.

Material And Methods: Prototypes of neck devices were developed on the Ender 2v2 3D printer («Shenzhen Creality 3D Technology Co., Ltd.

Evaluating the Usage of Janus Kinase Inhibitors in Rheumatology and Its Impact on Cardiovascular Risk.

Background/purpose Janus kinase (JAK) inhibitors have been widely used in treating rheumatological conditions like rheumatoid arthritis (RA) and psoriatic arthritis (PsA). Despite their efficacy, there are concerns regarding major adverse cardiovascular events (MACE) and venous thromboembolism (VTE) associated with JAK inhibitors. This study aimed to evaluate the risk of MACE, VTE, and the impact on lipid profiles in patients being treated with JAK inhibitors.

A Case of Primary Biliary Cholangitis in a Patient With Multiple Sclerosis.

Multiple sclerosis (MS) is a chronic inflammatory disease that causes demyelination in the brain and spinal cord, leading to significant neurological disability in young adults. Patients with MS are predisposed to other autoimmune disorders, though the co-occurrence of MS and primary biliary cholangitis (PBC) is rare. PBC is an autoimmune liver disease that affects bile ducts, leading to cholestasis and liver cirrhosis, predominantly in women aged over 40 years.