VFEND® (voriconazole)-associated hypoglycaemia without identified drug interaction.

To report the first case of severe hypoglycaemia episodes related to voriconazole, involving neither over dosage nor any identified interaction with hypoglycaemic drugs. A 51-year-old man developed faints without loss of consciousness, with sweating in the morning for 3-4 days and low blood glucose, about 1 month after initiating voriconazole therapy. Hypoglycaemia was diagnosed and the patient required permanent intravenous glucose solutions for 8 days after voriconazole was stopped, after which glycaemia remained normal.

[Alcoholemia and traumatology in S.A.M.U. 42].

This work was carried out over a year on all the wounded patients picked up by the S.A.M.