Publications by authors named "M Lynn Savoie"

The presence of elevated concentrations of smoke-derived volatile phenols (and their glycoconjugates) in wine after grapevine exposure to wildfire smoke can give wine unpleasant smoky and ashy characters. To date, options for remediation of 'smoke taint' are limited, therefore, this study evaluated the potential for a commercially developed molecularly imprinted polymer (MIP) to remove smoke taint compounds from wine. A single-solute adsorption study was conducted in model wine and demonstrated adsorption of guaiacol, phenol and m-cresol by a diverse range of binding sites on the MIP surface.

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This study investigates the flow field around a finite rectangular prism using both experimental and computational methods, with a particular focus on the influence of the turbulence approach adopted, the mesh resolution employed, and different subgrid length scales. Ten turbulence modelling and simulation approaches, including both 'scale-modelling' Reynolds-Averaged Navier-Stokes (RANS) models and 'scale-resolving' Delayed Detached Eddy Simulation (DDES), were tested across six different mesh resolutions. A case with sharp corners allows the location of the flow separation to be fixed, which facilitates a focus on the separated flow region and, in this instance, the three-dimensional interaction of three such regions.

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Background: We report results from the national CLEAR (Canadian Leadership on Antimicrobial Real-Life Usage) registry on the usage of ceftolozane/tazobactam in Canada from 2022 to 2024.

Research Design And Methods: The authors reviewed the final data using the national ethics approved CLEAR study. Thereafter, the literature is surveyed regarding the usage of ceftolozane/tazobactam to treat patients with HABP and VABP via PubMed (up to May 2024).

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Prochlorococcus marinus, the smallest picocyanobacterium, comprises multiple clades occupying distinct niches, currently across tropical and sub-tropical oligotrophic ocean regions, including Oxygen Minimum Zones. Ocean warming may open growth-permissive temperatures in new, poleward photic regimes, along with expanded Oxygen Minimum Zones. We used ocean metaproteomic data on current Prochlorococcus marinus niches, to guide testing of Prochlorococcus marinus growth across a matrix of peak irradiances, photoperiods, spectral bands and dissolved oxygen.

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Article Synopsis
  • - The study analyzed how different types of donors affect outcomes of hematopoietic cell transplantation (HCT) in patients with myelofibrosis, finding that the use of haploidentical donors rose significantly from 3% in 2013 to 19% in 2019.
  • - Among 1,032 patients with chronic-phase myelofibrosis, matched sibling donor HCTs showed better overall survival in the first three months compared to haploidentical and matched unrelated donor HCTs, with notably lower rates of graft failure.
  • - While matched sibling donors had superior early outcomes, there were no significant differences in long-term survival or disease-free survival among the different donor types, suggesting hap
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