Electrochemical sensor based on tadpole-shaped Au nanostructures supported on TiO: Enhanced detection of nicotine in electronic cigarettes and clinical samples.

Nicotine (NIC) detection is vital for monitoring its presence in various environments, including tobacco products, electronic cigarettes, and clinical samples; NIC's widespread use and health implications necessitate precise and reliable detection methods as it is linked to diseases such as lung cancer and vascular disorders. In this study, we developed and characterized Au tadpole-like nanostructures immobilized onto titanium oxide (TiO) to provide a cost-effective and sensitive NIC detection material. The comprehensive characterization of the composite used transmission electron microscopy (TEM), X-ray photoelectron spectroscopy (XPS), and X-ray diffraction (XRD), showing the robustness of the synthesis.

Spatial Profiling Reveals Equivalence-Derived Molecular Signatures of Brain Mimicry and Adaptation in Breast Cancer Brain Metastases.

Brain metastases (BrMets), common for advanced-stage breast cancer patients, are associated with poor median survival and accompanied by severe neurologic decline. Halting the progression of breast cancer brain metastases (BCBMs) may require modulation of the tumor microenvironment (TME), yet little is known about the impact of the primary breast TME on brain tropism, or how, once there, metastatic breast cancer cells coexist with brain-resident cells (e.g.

Survival analysis of a 16-year cohort of follicular lymphoma patients receiving systemic treatment in Brazil.

Introduction: Follicular lymphoma (FL) is a common type of non-Hodgkin lymphoma that is incurable but often follows an indolent course. While survival is improving thanks to advances in diagnosis, supportive care, and new therapies, understanding outcomes and their impact on overall survival is still limited. There are few studies on FL in Brazil, so this study aims to evaluate the patient's profile, morbidity and mortality treated by the Brazilian national health service (SUS) and evaluate risk factors associated with treatment failure.

Identification of Novel HLA-DQA1 and -DQB1 Alleles: DQA1*05:118 and DQB1*03:01:01:73.

Description of the novel HLA-DQA1*05:118 and -DQB1*03:01:01:73 alleles.

Structure and Morphological Properties of Cobalt-Oxide-Based (CoO) Materials as Electrodes for Supercapacitors: A Brief Review.

Over the past 15 years, there has been a significant increase in the search for environmentally friendly energy sources, and transition-metal-based energy storage devices are leading the way in these new technologies. Supercapacitors are attractive in this regard due to their superior energy storage capabilities. Electrode materials, which are crucial components of supercapacitors, such as cobalt-oxide-based electrodes, have great qualities for achieving high supercapacitor performance.