Medial facetectomy in recurrent lumbar nerve root compression.

This study investigated the outcome of medial facetectomy in reoperations after a previous discectomy. In a consecutive series of 98 patients with varying combinations of disc herniation, lateral stenosis, and scar, a good or moderate outcome was reached in 57% of the patients. Scar as an operative finding was a significant factor for poor outcome, especially in patients with preoperative symptoms for >1 year.

Lumbar paraspinal muscle function, perception of lumbar position, and postural control in disc herniation-related back pain.

Study Design: A follow-up study evaluating postural control, lumbar movement perception, and paraspinal muscle reflexes in disc herniation-related chronic low back pain (LBP) before and after discectomy.

Objectives: To assess the effect of discectomy on postural control, lumbar perception, and reflex activation of paraspinal muscles during sudden upper limb loading.

Summary Of Background Data: Impaired muscle function, postural control, and lumbar proprioception have been observed in LBP.

Microvascular myocutaneous flaps in the lumbosacral area using the iliac artery and vein as recipient vessels.

Lumbosacral tissue defects are usually closed with local flaps. Sometimes in large high-situated defects free microvascular flaps are used. However, finding a suitable recipient vessel for microvascular anastomosis in this region is difficult.

Changed lamellipodial extension, adhesion plaques and migration in epidermal keratinocytes containing constitutively expressed sense and antisense hyaluronan synthase 2 (Has2) genes.

Hyaluronan is a major component of the epidermal extracellular matrix, is actively synthesized by keratinocytes and shows fast matrix turnover in the stratified epithelium. We probed the importance of hyaluronan synthesis in keratinocytes by establishing cell lines carrying the exogenous hyaluronan synthase 2 (Has2) gene in sense and antisense orientations to increase and decrease their hyaluronan synthesis, respectively. Compared with cell lines transfected with the vector only, most clones containing the Has2 sense gene migrated faster in an in vitro wounding assay, whereas Has2 antisense cells migrated more slowly.

Disc herniation-related back pain impairs feed-forward control of paraspinal muscles.

Study Design: A comparative study of lumbar paraspinal muscle reflexes during sudden upper limb loading in healthy control subjects and patients with sciatica.

Objectives: To assess reflex activation of paraspinal muscles during sudden upper limb loading.

Summary Of Background Data: Sudden upper limb loading and upper limb voluntary movements cause reflex activation of trunk muscles.