Publications by authors named "M Lundholm"

Article Synopsis
  • - Primary adrenal insufficiency is a rare but serious condition that leads to a dangerous lack of cortisol and aldosterone, risking acute health issues like adrenal crisis.
  • - Diagnosis is often delayed or confused with secondary adrenal insufficiency, which can lead to critical health consequences.
  • - Early detection and proper treatment are crucial for improving health outcomes and enhancing the quality of life for affected patients.
View Article and Find Full Text PDF

Objective: Incidental radiographic findings of an empty sella are prevalent in up to 35% of the general population. While empty sella was initially considered clinically insignificant, a subset of patients exhibits endocrine or neuro-ophthalmologic manifestations which are diagnostic of empty sella syndrome (ESS). Recent studies suggest that more patients are affected by ESS than previously recognized, necessitating a deeper understanding of this condition.

View Article and Find Full Text PDF
Article Synopsis
  • Hyperglycemia is frequently seen in hospitalized patients and is typically treated with fixed insulin doses.
  • The 2022 guidelines from the Endocrine Society offer updated recommendations for managing hyperglycemia specifically in noncritically ill patients.
  • These guidelines introduce the use of new diabetes technologies, along with alternative insulin and noninsulin treatment options.
View Article and Find Full Text PDF

MicroRNAs (miRNAs) are aberrantly expressed in prostate cancer (PC), but comprehensive knowledge about their levels and function in metastatic PC is lacking. Here, we explored the differential expression of miRNA profiles during PC progression to bone metastasis, and further focused on the downregulation of miRNA-23c and -4328 and their impact on PC growth in experimental models. Using microarray screening, the levels of 1510 miRNAs were compared between bone metastases ( = 14), localized PC ( = 7) and benign prostate tissue ( = 7).

View Article and Find Full Text PDF