The Role of Religious Involvement as a Moderator of Perceived Health and Somatic Anxiety Among Hispanic Seventh-Day Adventists During COVID-19.

This study investigated whether the relationship between perceived health and somatic anxiety is moderated by religious involvement among a sample of Hispanic Seventh-day Adventists (n = 365) during the COVID-19 pandemic. Using PROCESS moderation analysis, we examined the interaction between perceived health and religious involvement on somatic anxiety. Results indicated a significant interaction effect, suggesting that the inverse relationship between perceived health and somatic anxiety was stronger when religious involvement was present.

Unusual high fluorescence of a 7,7'-diazaisoindigo derivative: A photophysical study.

7,7'-Diazaisoindigos are π-conjugated compounds but with poor luminescence properties. Their poor luminescence is generally attributed to the twisting around the central C-C bond in the excited state which favors non-radiative decay. We have found an unusual high fluorescence quantum yield (Φ ≈ 15 %) in a N,N‑Octyl-7,7'-diazaisoindigo derivative incorporating two triphenylamine (TPA) subunits at 5,5'-positions (called compound 12).

Role of the Lactide:Glycolide Ratio in PLGA Nanoparticle Stability and Release under Lysosomal Conditions for Enzyme Replacement Therapy of Lysosomal Storage Disorders.

Prior studies demonstrated that encapsulation in poly(lactic-co-glycolic acid) (PLGA) nanoparticles (NPs) enhanced the delivery of enzymes used for replacement therapy (ERT) of lysosomal storage disorders (LSDs). This study examined how the copolymer lactide:glycolide ratio impacts encapsulation, physicochemical characteristics, stability, and release under lysosomal conditions. Hyaluronidase, deficient in mucopolysaccharidosis IX, was encapsulated in NPs synthesized using 50:50, 60:40, or 75:25 lactide:glycolide copolymers.

Manufacture of Mesoporous Silicon Microparticles (MSMPs) as Adjuvants for Vaccine Delivery.

The advent of computational approaches has accelerated the identification of vaccine candidates like epitope peptides. However, epitope peptides are usually very poorly immunogenic and adequate platforms are required with adjuvant capacity to verity immunogenicity and antigenicity of vaccine subunits in vivo. Silicon microparticles are being developed as potential new adjuvants for vaccine delivery due to their physicochemical properties.