Publications by authors named "M Luderer"
Treatment of attention-deficit/ hyperactivity disorder (ADHD) in patients with a substance use disorder (SUD) and comorbid ADHD (SUD +ADHD) may have positive effects on the outcome of both conditions, but controversy exists regarding the preferred ADHD treatment in these patients. Little is known about the treatments that are provided for these patients in routine addiction care practice and the factors that are associated with treatment provision. To describe the treatments provided in everyday clinical practice and to explore factors associated with ADHD treatment provision in patients with SUD +ADHD.
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- Disulfiram, although no longer approved for use in Germany over a decade ago, is still prescribed by many practitioners within the "Network for Alcohol Aversive Pharmacotherapy" (NAP), highlighting its ongoing relevance in treating alcoholism.
- A survey conducted from 2019 to 2023 revealed that 1,579 treatment cases were reported, with 152 patients having drinking events, though most resulted in no serious complications.
- The study found disulfiram to be generally well-tolerated, with common side effects including body odor and fatigue; importantly, many patients also had comorbid psychiatric conditions, and treatment often included additional therapies.
Article Synopsis
- - ADHD is commonly found in individuals with alcohol use disorder (AUD), but most studies overlook hyperactivity as a key symptom; this study examines ADHD symptoms, executive functioning, mind wandering, and quality of life in different groups.
- - Results showed that individuals with AUD displayed higher inattention and impulsivity compared to those with ADHD alone, while hyperactivity was notably higher in those with both ADHD and AUD.
- - The study highlights that questionnaires are better for assessing ADHD symptoms than the QbTest, and suggests a need for better screening and treatment strategies for individuals with both ADHD and AUD due to their lower quality of life.
Treatment resistance in alcohol use disorders (AUD) is a major problem for affected individuals and for society. In the search of new treatment options, few case studies using deep brain stimulation (DBS) of the nucleus accumbens have indicated positive effects in AUD. Here we report a double-blind randomized controlled trial comparing active DBS ("DBS-EARLY ON") against sham stimulation ("DBS-LATE ON") over 6 months in n = 12 AUD inpatients.
View Article and Find Full Text PDFBackground: Substance use disorders (SUD) often co-occur with attention deficit hyperactivity disorder (ADHD). Although the short-term effects of some specific interventions have been investigated in randomized clinical trials, little is known about the long-term clinical course of treatment-seeking SUD patients with comorbid ADHD.
Aims: This paper presents the protocol and baseline clinical characteristics of the International Naturalistic Cohort Study of ADHD and SUD (INCAS) designed and conducted by the International Collaboration on ADHD and Substance Abuse (ICASA) foundation.