[The stage of portal blood flow in patients with hemoblastosis combined with chronic hepatitis].

109 patients with hemoblastosis (HB) were examined. Average age was 31.8 +/- 1.

One-step assembly of carbamoyl-substituted heteroannelated [1,4]thiazepines.

We present a convenient synthesis of novel heteroaryl-fused 3-oxo-1,4-thiazepine-5-carboxamides and 5-oxo-1,4-thiazepine-3-carboxamides using a modification of four-component Ugi condensation. We demonstrate the usefulness and versatility of the developed approach for the synthesis of variously substituted compounds and discuss the scope and limitations of the chemistry involved.

[Features of heart function and morphology in chronic organic solvents intoxication].

Patients with chronic organic solvents intoxication are characterized by left ventricle hyperfunction mostly isometric type, with left ventricle diastole disordered due to impaired both passive filling and active relaxation, given the chamber geometry is normal and hypokinetictype hemodynamics is prevalent. Phase analysis of left heart mechanic activity in patients with chronic organic solvents intoxication demonstrated I degree hypodinamia syndrome and left ventricle outlet stenosis.