Publications by authors named "M Lopez-Gomez"
Background: Nutrients, including bioactive natural compounds, have been demonstrated to affect key metabolic processes implicated in tumor growth and progression, both in preclinical and clinical trials. Although the application of precision nutrition as a complementary approach to improve cancer treatments is still incipient in clinical practice, the development of powerful "omics" techniques has opened new possibilities for delivering nutritional advice to cancer patients. Precision nutrition may contribute to improving the plasticity and function of antitumor immune responses.
View Article and Find Full Text PDFObjectives: To describe the clinical spectrum of VEXAS syndrome in patients managed by rheumatology units and analyze genotype-phenotype correlations.
Methods: A multicentre, cross-sectional, retrospective study was conducted across 126 Spanish hospitals. Patients with VEXAS syndrome diagnosed between December 2020 and January 2024 were included.
Introduction: We conducted a comprehensive comparative analysis of the Okazaki, Umehara, and American College of Rheumatology/European League Against Rheumatism (ACR/EULAR) classification criteria for diagnosing immunoglobulin G4-related disease (IgG4-RD).
Materials And Methods: A retrospective study was conducted in a single tertiary hospital, using expert clinical judgment as the gold standard. We compared the diagnostic accuracy of the Okazaki, Umehara, and ACR/EULAR criteria in a cohort of 41 patients with suspected IgG4-RD.
Cancer stem cells (CSC) in colorectal cancer drive intratumoral heterogeneity and distant metastases. Previous research from our group showed that CSCs can be easily detected by autofluorescence (AF). The aim of the present study was to evaluate the potential role of AF CSCs as a prognostic biomarker for colorectal cancer relapse.
View Article and Find Full Text PDFArticle Synopsis
- The study investigates the prevalence of a microorganism related to gastric adenocarcinoma (AC) in patients with esophageal carcinoma, noting that its role seems protective rather than harmful in this context.
- It involved a retrospective review of 89 esophageal carcinoma patients, revealing that only 4.5% had a prior infection and most were at advanced cancer stages when diagnosed.
- The findings suggest that the very low prevalence of infection among these patients, coupled with high rates of proton pump inhibitor usage, may indicate a protective effect against esophageal cancer.