Clinical practice recommendations for kidney involvement in tuberous sclerosis complex: a consensus statement by the ERKNet Working Group for Autosomal Dominant Structural Kidney Disorders and the ERA Genes & Kidney Working Group.

Tuberous sclerosis complex (TSC) is an autosomal dominant disorder characterized by the presence of proliferative lesions throughout the body. Management of TSC is challenging because patients have a multifaceted systemic illness with prominent neurological and developmental impact as well as potentially severe kidney, heart and lung phenotypes; however, every organ system can be involved. Adequate care for patients with TSC requires a coordinated effort involving a multidisciplinary team of clinicians and support staff.

[Peracetic acid: alternative to the sterilization of bronchofibroscopes].

The Steris system for cold sterilization with peracetic acid was evaluated by effecting a series of contaminations of a fiberoptic bronchoscope (FB) with specimens of Pseudomonas aeruginosa, Acinetobacter baumanii and Mycobacterium kansasi. The FB was contaminated 24 times, 8 times by each microorganism, using specimens containing more than 10(8) cfu/ml. After fixing the secretions on the FB and washing it with enzyme soap, the BF was sterilized.

[A study of arteriosclerotic disease and of ischemic cardiopathy in particular and the associated risk factors in the Autonomous Basque Community. The Euzkadi project].

The aim of the Euzkadi Project was to know the prevalence rate of cardiovascular disease and the high risk factors (hypertension, hypercholesterolemia and cigarette smoking) in the Basque Country to carry out an intervention trials to reduce these factors if we have collaboration of the Public Health Service. We have studied a sample of 4,800 men, 25-64 years old, randomly selected (1,600 men in each province), the examination was done by cardiologist using the cardiovascular questionnaire by Blackburn and Rose, the cholesterol was tested in WHO Collaborating Lipid Reference Center (Prague) and the electrocardiogram was studied by Minnesota Code. The rate of Atherosclerotic disease was 69%, coronary heart disease 49% (12% angina típica, 9% angina atípica and 28% myocardial infarction), stroke 7%, and peripheral vascular disease 13%.