Validation of basophil CD164 upregulation for pollen allergy diagnosis.

The aim of the study was to evaluate the sensitivity and specificity of allergen-induced basophil CD164 upregulation in patients with seasonal allergic rhinitis caused by allergy to grass pollens. This study was performed in 24 patients with allergy to grass pollens, and in 25 healthy controls. The protocol for allergen-induced basophil CD164 upregulation consisted of whole blood samples processing and staining with anti-CCR3/anti-CD164 antibodies added to a buffer at the beginning of stimulation.

A new variant of the basophil activation test for allergen-induced basophil CD63 upregulation. The effect of cetirizine.

Objective: The aim of our study was to determine the diagnostic usefulness of a newly developed basophil activation test (BAT) in patients allergic to Dermatophagoides pteronyssinus and pollens. We also analyzed the influence of cetirizine on CD63 upregulation. This popular antihistamine strongly inhibits skin tests, but its impact on BAT sensitivity remains unknown and deserves at least preliminary determination.

Influence of hyperosmotic conditions on basophil CD203c upregulation in patients with food-dependent exercise-induced anaphylaxis.

Increased in vitro basophil activation in buffers of slightly elevated osmolarity in 2 cases of food-dependent exercise-induced anaphylaxis is presented. These data may suggest the importance of basophil activation degree in pathogenesis of this life threatening syndrome.

[Efficacy and safety of specific immunotherapy of upper airways allergic diseases caused by allergy to mites].

Aim Of The Study: The aim of this study was to evaluate the efficacy and safety of 3 years oral specific immunotherapy in patients with perannial allergic rhinitis and bronchial asthma caused by allergy to mites.

Material And Methods: Fifteen patients with allergic perannial rhinitis entered the study. Ten of them suffered also from bronchial asthma.

[Use of selected parameters of nasal lavage fluid in asthma severity monitoring].

Unlabelled: Allergic inflammation is a chronic disorder underlying asthma and allergic rhinitis. There is a theory "one system--one disease" connecting these two atopic diseases. Eosinophil is a major effector cell in both processes.