Publications by authors named "M Limaye"
Objective: We sought to create a machine learning (ML) model to identify variables that would aid in the prediction of surgical morbidity in cases of placenta accreta spectrum (PAS).
Study Design: A multicenter analysis including all cases of PAS identified by pathology specimen confirmation, across five tertiary care perinatal centers in New York City from 2013 to 2022. We developed models to predict operative morbidity using 213 variables including demographics, obstetrical information, and limited prenatal imaging findings detailing placental location.
Article Synopsis
- Anti-Hu antibodies are commonly linked to paraneoplastic syndromes (PNS), particularly associated with cancers like small cell lung cancer, breast cancer, and lymphoma.
- A case study describes a 65-year-old woman with neurological symptoms and imaging revealing a mass, alongside positive anti-Hu antibody tests, but no definitive diagnosis of the primary tumor.
- PNS is challenging to diagnose and manage; treating the underlying cancer and immune modulation are essential for improving patient outcomes, highlighting the need for early diagnosis and a multidisciplinary approach.
Article Synopsis
- This study explored the link between fetal fraction (amount of fetal DNA in the mother's blood) and low birth weight in twin pregnancies, aiming to understand how these factors relate, especially in the first trimester.
- The analysis included 1,041 twin pregnancies and found that no significant differences in fetal fraction existed between twins with low birth weight (<10th percentile) and those with normal birth weight (≥10th percentile).
- Ultimately, the results indicated no correlation between high or low fetal fractions and low birth weight, suggesting that fetal fraction is not a reliable predictor of adverse birth weight outcomes in twin pregnancies.
Article Synopsis
- - A rare case of a vein of Galen aneurysmal malformation (VGAM) was diagnosed in a fetus during a monochorionic-diamniotic twin pregnancy at 28 weeks using color Doppler ultrasonography.
- - The affected fetus showed severe heart issues and was delivered at 32 weeks due to abnormal heart rates, but brain imaging after birth revealed serious neurological damage, leading to no postnatal treatment.
- - This case is notable as it is the first documented instance of prenatal VGAM diagnosis in such a twin pregnancy, highlighting the complexities involved in deciding when to deliver.
Background: Biologically active cervical glands provide a mucous barrier while influencing the composition and biomechanical strength of the cervical extracellular matrix. Cervical remodeling during ripening may be reflected as loss of the sonographic cervical gland area. As sonographic cervical length remains suboptimal for universal screening, adjunctive evaluation of other facets of the mid-trimester cervix may impart additional screening benefit.
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