Publications by authors named "M Liebregts"

Introduction: High-density (HD) substrate mapping may increase success of catheter ablation targeting ventricular tachycardia (VT). However, despite its use, recurrent VT is not uncommon. We aim to investigate factors that are associated with outcomes after HD mapping-guided substrate ablation procedures for VT in patients with ischemic cardiomyopathy.

View Article and Find Full Text PDF

The American approach to predicting sudden cardiac death (SCD) in patients with hypertrophic cardiomyopathy diverges from the European method in that it relies on major risk factors independently justifying the implantation of an implantable cardioverter-defibrillator for primary prevention, whereas the European approach uses a mathematical equation to estimate a 5-year risk percentage. The aim of this review is to outline the differences between the American and European guidelines and to show how they have arisen. Furthermore, it will provide insight into the future of SCD risk prediction in patients with hypertrophic cardiomyopathy.

View Article and Find Full Text PDF

Background: The current ACC/AHA guidelines on hypertrophic cardiomyopathy (HCM) caution that alcohol septal ablation (ASA) might be less effective in patients with left ventricular outflow tract obstruction (LVOTO) ≥ 100 mm Hg.

Methods: We used a multinational registry to evaluate the outcome of ASA patients according to baseline LVOTO.

Results: A total of 1346 ASA patients were enrolled and followed for 5.

View Article and Find Full Text PDF
Article Synopsis
  • Atrioventricular block is a common complication following alcohol septal ablation (ASA) in patients with hypertrophic obstructive cardiomyopathy, leading to some requiring a permanent pacemaker (PPM).
  • In a study involving 1,814 patients using the Euro-ASA registry, 9.4% underwent PPM implantation within 30 days after the procedure, with a follow-up averaging 4 years.
  • Long-term outcomes revealed that while survival and functional class were similar between groups, those with PPM had a lower left ventricular outflow gradient and lower likelihood of needing further interventions.
View Article and Find Full Text PDF