Background: Phage therapy, a treatment utilizing bacteriophages to combat bacterial infections, is gaining attention as a promising alternative to antibiotics, particularly for managing antibiotic-resistant bacteria. This study aims to provide a comprehensive review of phage therapy by examining its safety, efficacy, influencing factors, future prospects, and regulatory considerations. The study also seeks to identify strategies for optimizing its application and to propose a systematic framework for its clinical implementation.
View Article and Find Full Text PDFHerein, we present a strategy for the controlled assembly of single-walled carbon nanotube (SWCNT) linear junctions mediated by DNA as a functional linker. We demonstrate this by employing SWCNTs of two different chiralities via the specific design of DNA sequences and chiral selection. Streptavidin and AuNP labeling of the SWCNT sidewalls demonstrate the presence of two different chirality within each individual CNT-DNA-CNT junction.
View Article and Find Full Text PDFThis article introduces a novel approach to detecting honey adulteration by combining ultra-fast gas chromatography (UF-GC) with advanced machine learning techniques. Machine learning models, particularly support vector regression (SVR) and least absolute shrinkage and selection operator (LASSO), were applied to predict adulteration in orange blossom (OB) and sunflower (SF) honeys. The SVR model achieved R values above 0.
View Article and Find Full Text PDFFetal mediastinal teratomas are rare tumors that can lead to serious complications such as fetal hydrops and intrauterine fetal death. Early prenatal diagnosis is critical in patient counseling, management, and preparation for postnatal interventions. In this report, we present the case of a 27-year-old woman in the second trimester of a dichorionic diamniotic twin pregnancy, in which the presenting fetus was diagnosed with a mediastinal teratoma and subsequently developed fetal hydrops, leading to intrauterine death.
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