Publications by authors named "M Leshno"

Objective: Given the good prognosis of low-risk papillary thyroid microcarcinomas (lrPTMCs), accurate risk stratification is valuable to optimize management: active surveillance (AS) vs. hemithyroidectomy (HT). BRAF positive lrPTMC is associated with increased recurrence risk; hence, AS was suggested for mutation-negative lrPTMC.

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Background: Chromosomal microarray analysis (CMA) has been central to prenatal genetic diagnosis, detecting copy number variants with a ∼1% yield in low-risk cases. Next-generation sequencing (NGS), including exome sequencing (ES), enhances diagnostic capabilities with higher yields (8.5-10%) but at greater cost and complexity.

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  • The study investigates the link between ADHD and glycemic control in adults with type 2 diabetes (T2DM), emphasizing the importance of treatment persistence.
  • Data were collected from Maccabi Healthcare Services' electronic records (2010-2020), comparing patients with T2DM and ADHD to those without, using various statistical methods to analyze HbA1c levels.
  • Results show that individuals with ADHD and T2DM have significantly poorer glycemic control, indicating a need for further research to improve care and outcomes for these patients.
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  • A study was conducted to compare two preparation protocols for patients with Crohn's disease who ingested a patency capsule (PC) to assess its effectiveness in reducing failed PC rates.
  • The pro-motility group, which followed a specific diet and took medication, showed a significantly lower failed PC rate (12.0%) compared to the control group (24.7%).
  • Findings suggest that the pro-motility protocol not only enhances the success rate of the patency test but may also help minimize the risk of complications related to capsule retention.
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Unlabelled: Fecal microbial transplantation (FMT) is the delivery of fecal microbiome, isolated from healthy donors, into a patient's gastrointestinal tract. FMT is a safe and efficient treatment for recurrent infection. Donors undergo strict screening to avoid disease transmission.

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